Author

Arox Wadson Kamng’ona

Kamuzu University of Health SciencesORCID 0000-0002-0841-7586Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:clustering· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Chrispin ChaguzaiD· 2 shared Neil FrenchiD· 2 shared Robert S. HeydermaniD· 2 shared Akuzike Kalizang’omaiD· 1 shared Aras KadiogluiD· 1 shared Brenda Kwambana-AdamsiD· 1 shared Chikondi PenoiD· 1 shared Comfort Brown· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

Chrispin ChaguzaORCID

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2 papers

Recent·Most cited

Expansion of pneumococcal serotype 23F and 14 lineages with genotypic changes in capsule polysaccharide locus and virulence gene profiles post introduction of pneumococcal conjugate vaccine in Blantyre, Malawi

Rory J. Cave, Akuzike Kalizang’oma, Chrispin Chaguza, Thandie S. Mwalukomo, Arox Wadson Kamng’ona, Comfort Brown, Jacquline Msefula, Farouck Bonomali, Roseline Nyirenda, Todd D. Swarthout, Brenda Kwambana-Adams, Neil French, Robert S. Heyderman

The paper analyzes whole-genome sequences of pneumococcal isolates in Malawi to show expansion of vaccine serotype lineages with genetic changes in capsule and virulence genes post-PCV13 introduction.

Microbial Genomics · Jun 19, 2024Peer-reviewedMicrobiology

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data

Chrispin Chaguza, Ellen Heinsbroek, Rebecca A. Gladstone, Terence Tafatatha, Maaike Alaerts, Chikondi Peno, Jennifer Cornick, Patrick Musicha, Naor Bar‐Zeev, Arox Wadson Kamng’ona, Aras Kadioglu, Lesley McGee, William Paul Hanage, Robert F. Breiman, Robert S. Heyderman, , Stephen D. Bentley

This paper analyzes pneumococcal carriage genomic data before and after PCV13 introduction, showing reduced vaccine-type strains and limited serotype replacement.

Clinical Infectious Diseases · May 15, 2019Peer-reviewedGenomics