Neil French

The paper shows that accessory capsular genes in Streptococcus pneumoniae enhance fitness, pathogenicity, and immune evasion without capsule switching.

This study shows that the LytSR two-component system in Streptococcus agalactiae enhances vaginal colonization and virulence by promoting biofilm formation and inflammatory responses.

The paper analyzes whole-genome sequences of pneumococcal isolates in Malawi to show expansion of vaccine serotype lineages with genetic changes in capsule and virulence genes post-PCV13 introduction.

The paper identifies reduced host transcriptomic signatures for tuberculosis using microarray data and validates them with digital PCR, showing high accuracy in distinguishing TB from other conditions and latent TB.

This study performs a pan-GWAS of Streptococcus agalactiae strains to identify lineage-specific genes linked to virulence and niche adaptation across different host environments.

This paper analyzes pneumococcal carriage genomic data before and after PCV13 introduction, showing reduced vaccine-type strains and limited serotype replacement.

This study identifies 43 genes associated with invasive pneumococcal disease using whole genome sequence data and a random forest machine-learning algorithm across three geographically distinct datasets.