Author

Maaike Alaerts

University of AntwerpORCID 0000-0002-1376-3635Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Dean EverettiD· 2 shared Jennifer CornickiD· 2 shared Lesley McGeeiD· 2 shared Rebecca A. GladstoneiD· 2 shared Robert F. BreimaniD· 2 shared Stephen D. BentleyiD· 2 shared William Paul HanageiD· 2 shared Abdullah W. Brooks· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Dean EverettORCID

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Author profile →

3 papers

Recent·Most cited

CRISPR-Engineered hiPSC-derived Cardiomyocytes Reveal Divergent Responses to Loss and Defective Processing of A-type Lamins

Lauran Vandeweyer, E Garrido-Huescar, Mirthe Vandenputte, Bert Vandendriessche, Maaike Alaerts, Laura Ordovás, Bart Loeys, Winnok Harald De Vos

This study compares the effects of lamin A/C loss and defective prelamin A processing in cardiomyocytes using CRISPR-engineered hiPSC-derived cells, revealing shared and distinct stress responses.

bioRxiv · Jun 30, 2026 · PreprintCell Biology

The role of interspecies recombinations in the evolution of antibiotic resistant pneumococci

Joshua C D'Aeth, Mark PG van der Linden, Lesley McGee, Herminia de LENCASTRE, Paul Turner, Jae-Hoon Song, Stephanie W. Lo, Rebecca A. Gladstone, Raquel Sá‐Leão, Kwan Soo Ko, William Paul Hanage, Robert F. Breiman, Bernard Beall, Stephen D. Bentley, Nicholas J. Croucher, , David William Cleary

The paper reconstructs the evolutionary histories of antibiotic-resistant pneumococcal lineages PMEN3 and PMEN9, showing how interspecies recombination contributes to antibiotic resistance and serotype switching.

eLife · Jul 14, 2021Peer-reviewedGenomics

Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data

Chrispin Chaguza, Ellen Heinsbroek, Rebecca A. Gladstone, Terence Tafatatha, Maaike Alaerts, Chikondi Peno, Jennifer Cornick, Patrick Musicha, Naor Bar‐Zeev, Arox Wadson Kamng’ona, Aras Kadioglu, Lesley McGee, William Paul Hanage, Robert F. Breiman, Robert S. Heyderman, , Stephen D. Bentley

This paper analyzes pneumococcal carriage genomic data before and after PCV13 introduction, showing reduced vaccine-type strains and limited serotype replacement.

Clinical Infectious Diseases · May 15, 2019Peer-reviewedGenomics