Author

Charles‐Hugo Marquette

Centre National de la Recherche ScientifiqueORCID 0000-0002-0846-9941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Christophe BécaviniD· 2 shared Marie Deprez· 2 shared Adam L. HaberiD· 1 shared Agnes C. PaquetiD· 1 shared Ahmad N. NabhaniD· 1 shared Alex Sountoulidis· 1 shared Alexi McAdams· 1 shared Allon Zaneta Andrusivova· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenomics

Christophe BécavinORCID

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Author profile →

2 papers

Recent·Most cited

A single-cell atlas of the human healthy airways

Marie Deprez, Laure‐Emmanuelle Zaragosi, Marin Truchi, Christophe Bécavin, Sandra Ruiz García, Marie‐Jeanne Arguel, Magali Plaisant, Virginie Magnone, Kévin Lebrigand, Sophie Abélanet, Frédéric Brau, Agnes C. Paquet, Dana Pe’er, Charles‐Hugo Marquette, Sylvie Leroy, Pascal Barbry

The paper constructs a single-cell atlas of the human healthy airways using RNA sequencing data from 77,969 cells across 35 locations, revealing cell-type-specific gene expression patterns and cellular heterogeneity.

American Journal of Respiratory and Critical Care Medicine · Jul 29, 2020Peer-reviewedGenomics

Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells

Christoph Muus, Malte D. Luecken, Gökçen Eraslan, Avinash Waghray, Graham Heimberg, Lisa Sikkema, Yoshihiko Kobayashi, Eeshit Dhaval Vaishnav, Ayshwarya Subramanian, Christopher Smilie, Karthik A. Jagadeesh, Thu Elizabeth Duong, Evgenij Fiškin, Elena Torlai Triglia, Meshal Ansari, , Wenjun Yan

Across 1,176,683 airway and lung cells from 22 datasets, ACE2 rises with age, in males and in smokers' multiciliated cells, and is lowest in young children.

bioRxiv · Apr 19, 2020 · PreprintBioinformatics✦ In-depth digest