Frédéric Brau

This study shows that ether lipid remodeling during neuronal differentiation prevents ferroptosis by balancing pro- and anti-ferroptotic effects through vinyl ether bonds.

The paper uses 3D spheroid models to show filopodia-like protrusions help breast cancer cells invade by widening basement membrane pores.

This study shows glucocorticoids increase P-body numbers and alter mRNA translation fate based on transcript sequence features, not abundance.

The paper investigates how different human perilipins bind to lipid droplets by showing their varying affinities based on surface tension and lipid composition.

This study shows ASIC1a/ASIC2 channels in spinal neurons contribute to pain processing by modulating windup through calcium-dependent mechanisms.

This study shows that cocaine worsens HAND symptoms in an HIV mouse model by altering DNA methylation and gene expression, affecting neuronal and glial functions.

This study investigates a missense Fmr1 mutation in mice, showing increased spine density, synaptic defects, and cognitive deficits linked to Fragile X syndrome.

The paper introduces aiFACS, a technique for real-time functional analysis and sorting of cells, and applies it to study interneurons in Fragile X syndrome.

The paper constructs a single-cell atlas of the human healthy airways using RNA sequencing data from 77,969 cells across 35 locations, revealing cell-type-specific gene expression patterns and cellular heterogeneity.

The paper investigates how high-fat diet exposure increases hypothalamic inflammation and glial cell activity in mice, linking it to potential obesity risk.