Julia Eve Olivieri

Analysis of RNA processing directly from spatial transcriptomics data reveals previously unknown regulation

The paper applies RNA processing analysis methods to spatial transcriptomics data, identifying new spatially regulated RNA processing events in mouse tissues.

Mouse lemur transcriptomic atlas informs primate genes, mutations, physiology, and disease

This paper uses a mouse lemur transcriptomic atlas to identify new genes, splice junctions, and disease-related features, highlighting their relevance to primate biology and human disease.

The SpliZ generalizes "Percent Spliced In" to reveal regulated splicing at single-cell resolution

The paper introduces SpliZ and SpliZVD, statistical methods to detect regulated splicing in single-cell RNA-seq, revealing new cell-type-specific splicing events in human lung cells.

RNA splicing programs define tissue compartments and cell types at single cell resolution

The paper introduces SpliZ, a statistical method to detect cell-type-specific splicing regulation in single-cell RNA-seq data, finding 9.1% of genes show such regulation in human tissues.

Specific splice junction detection in single cells with SICILIAN

SICILIAN improves splice junction detection in scRNA-seq by assigning statistical confidence, enhancing accuracy and agreement with bulk data and biological replicates.

Pervasive additive and non-additive effects within the HLA region contribute to disease risk in the UK Biobank

The paper analyzes HLA allele associations with 677 phenotypes in the UK Biobank, identifying 88 replicated and 90 novel associations, and uncovering non-additive and homozygous effects on disease risk.

Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics

Global Biobank Engine enables browsing of genotype-phenotype relationships using biobank summary statistics from large cohorts like UK Biobank.