Marilyne Malbouyres

A zebrafish model of Bethlem myopathy reveals CaV1.1 as the missing link between collagen type VI deficiency and muscle dysfunction

This study uses a zebrafish model of Bethlem myopathy to show that collagen VI deficiency disrupts CaV1.1 function, leading to increased sarcoplasmic reticulum Ca2+ leak and muscle dysfunction.

Cranial suture integrity is maintained by Fgfr3 in zebrafish

This study shows Fgfr3 maintains cranial suture integrity in zebrafish by regulating osteogenesis and interacting with FGF, Wnt, and BMP signaling.

The myotendinous junction marker collagen XXII enables zebrafish postural control learning and optimal swimming performance through its force transmission activity

This study shows that col22a1 gene ablation in zebrafish leads to variable phenotypes in muscle function and movement, highlighting its role in force transmission and postural control.