Florence Ruggiero

This study identifies fibroblasts as key drivers of disease progression in Bethlem myopathy using a zebrafish model and single-nucleus RNA sequencing.

This study identifies matrisome signatures in quiescent and activated muscle stem cells using transcriptomic data, linking ECM gene expression to niche function and muscle repair.

This study uses a zebrafish model of Bethlem myopathy to show that collagen VI deficiency disrupts CaV1.1 function, leading to increased sarcoplasmic reticulum Ca2+ leak and muscle dysfunction.

This study shows Fgfr3 maintains cranial suture integrity in zebrafish by regulating osteogenesis and interacting with FGF, Wnt, and BMP signaling.

The paper identifies Collagen XV-B and Tenascin C as ECM components guiding motor axon growth through their dual topology and stiffness in zebrafish.

This study shows that col22a1 gene ablation in zebrafish leads to variable phenotypes in muscle function and movement, highlighting its role in force transmission and postural control.