Differential proteomic and metabolic remodelling of CD4⁺ and CD8⁺ T cells in mesenteric lymph nodes during colitis-associated colorectal cancer
Diego González‐Romero, Laura Spinelli, Pilar Fajardo, Ester Díaz‐Mora, Marta Gómez de Cedrón, Juan José Sanz‐Ezquerro, Doreen Ann Cantrell, Ana Cuenda
The paper uses mass spectrometry to analyze proteomic and metabolic changes in CD4⁺ and CD8⁺ T cells during colitis-associated colorectal cancer in mice, revealing distinct adaptations between the two cell types.
bioRxiv · Jan 27, 2026 · PreprintImmunology