Nicholas James Leeper

This study shows CD47 blockade reprograms the monocyte-macrophage axis in atherosclerosis, reducing inflammation and enhancing apoptotic cell clearance.

This study shows cancer increases atherosclerotic plaque vulnerability through pathological angiogenesis, and targets this pathway to prevent plaque destabilization.

This study identifies BST2 as a driver of vascular smooth muscle cell plasticity and macrophage-like phenotype switching in tumors, with implications for immunosuppression and therapy.

The paper uses single-cell ATAC-seq to analyze coronary artery cells from CAD patients, identifying regulatory mechanisms and risk variants associated with disease.