The paper presents a cost-effective NGS library preparation method for insect genomics using low DNA input and 96-well plates, showing it works with ethanol-stored DNA and improves efficiency with bead clean-up.

bioRxiv · Nov 24, 2023 · PreprintGenomics

Systematic prioritization of candidate genes in disease loci identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease

Adriaan van der Graaf, Maria Magdalena Zorro, Annique Claringbould, Urmo Võsa, Raúl Aguirre‐Gamboa, Chan Li, Joram Mooiweer, Isis Ricaño-Ponce, Zuzanna Borek, Frits Koning, Yvonne Kooy–Winkelaar, Ludvig Magne Sollid, Shuo‐Wang Qiao, Vinod Kumar, Yang Li, , Iris H. Jonkers

The paper identifies TRAFD1 as a master regulator of IFNγ signalling in celiac disease by systematically prioritizing candidate genes in disease loci using multiple computational methods.

Frontiers in Genetics · Jan 25, 2021Peer-reviewedGenetics

BraCeR: Reconstruction of B-cell receptor sequences and clonality inference from single-cell RNA-sequencing

Ida Lindeman, Guy Emerton, Lira Mamanova, Omri Snir, Krzysztof Polański, Shuo‐Wang Qiao, Ludvig Magne Sollid, Sarah Amalia Teichmann, Michael J. T. Stubbington

BraCeR reconstructs B-cell receptor sequences and infers clonality from scRNA-seq data without needing additional Rep-seq.

Nature Methods · Jul 20, 2018Peer-reviewedBioinformatics