Molecular BiologyCell ReportsPeer-reviewed
TRMT1L-catalyzed m22G27 on tyrosine tRNA is required for efficient mRNA translation and cell survival under oxidative stress.
Sseu-Pei Hwang, Han Liao, Katherine Barondeau…·Catherine Denicourt
This study identifies TRMT1L as the methyltransferase responsible for m22G27 modification on tRNA-Tyr-GUA, showing its role in translation efficiency and oxidative stress resistance.
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