GenomicsAnnals of the Rheumatic DiseasesPeer-reviewed
Time-resolved immune dynamics in rheumatoid arthritis under Methotrexate therapy
Teresa Preglej, Anela Tosevska, Marie Brinkmann…·Michael Markus Bonelli
This study uses scRNA-seq and immunophenotyping to analyze immune changes in RA patients on MTX, showing early restoration of naive T/B cells and reduced memory T cells, with plasmablasts as a potential biomarker.