Synthetic BiologybioRxivPreprint
Active site mutations of F420-dependent alkene reductases reverse stereoselectivity
Suk Woo Kang, James Antoney, David W. Lupton…·Colin J. Jackson
The paper investigates how active site mutations in FDOR enzymes affect stereoselectivity and reveals that a Tyr-Met mutation reverses stereoselectivity and alters hydrogenation mode.
DOI 10.1101/2023.02.21.529347