Author

Simon Turcotte

Centre Hospitalier de l’Université de MontréalORCID 0000-0002-0978-736XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Abdelhakim KhellafiD· 1 shared Alexandre Archambault-MarsaniD· 1 shared Ali KassabiD· 1 shared Anthony ParentiD· 1 shared Basile Tessier‐CloutieriD· 1 shared Camille Beaussier· 1 shared Cheng-Hsun Hsieh· 1 shared Dalia Baršytė-LovejoyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Abdelhakim KhellafORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 9, 2026

Spatial multi-omics resolve epithelium-fibroblast gradients and highlight NESTIN-NOTCH1-expressing subepithelial fibroblasts during human pancreatic tumorigenesis

Maëlle Batardière, Myriam Iliana Ibanez-Rios, Abdelhakim Khellaf…·Vincent Quoc‐Huy Trinh

This study uses spatial multi-omics to identify NESTIN-NOTCH1-expressing fibroblasts in IPMNs and their role in pancreatic tumorigenesis.

DOI 10.64898/2026.09.04.749182

humanspatial transcriptomics

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedSep 5, 2026

PRMT7 restricts CD8+ T cells expansion via the NF-κB pathway.

Nivine Srour, Kaixiu Luo, David Allard…·Stéphane Richard

This study identifies PRMT7 as a negative regulator of CD8+ T cell immunity and demonstrates a PROTAC degrader (MS54) that enhances anti-tumor responses by activating the NF-κB pathway.

1 citation

𝕏 PostBluesky