Ludmilla de Plater

Fluid transport properties dominate blastocyst expansion over mechanics

The paper investigates the role of osmotic pressure and mechanical stresses in blastocyst expansion using mouse embryos and finds that osmotic pressure differences dominate over mechanical stresses.

Mechanical strengthening of cell-cell adhesion during mouse embryo compaction

This study investigates how mechanical forces during mouse embryo compaction strengthen cell-cell adhesion by expanding Cdh1 adhesive rings without increasing bond density.

Ectopic activation of the polar body extrusion pathway triggers cell fragmentation in preimplantation embryos

This study identifies that ectopic activation of the polar body extrusion pathway during mitosis in preimplantation embryos triggers cell fragmentation through actomyosin contractility.

Zygotic contractility awakening during mouse preimplantation development

This study investigates how zygotic contractility awakens during mouse preimplantation development by analyzing cortical waves and cell size changes.

Multiscale analysis of single and double maternal-zygotic Myh9 and Myh10 mutants during mouse preimplantation development

This study examines the effects of Myh9 and Myh10 mutations on mouse preimplantation development using multiscale imaging, revealing that contractility is not essential for certain developmental processes.

Fracking and Ostwald ripening position the lumen of the mouse blastocyst

This study identifies hydraulic fracture of cell-cell contacts and directed coarsening of microlumens as mechanisms controlling lumen positioning in mouse blastocysts.