Stéphanie Descroix

The paper investigates the role of osmotic pressure and mechanical stresses in blastocyst expansion using mouse embryos and finds that osmotic pressure differences dominate over mechanical stresses.

This study identifies biomechanical changes in the tubular basement membrane as drivers of cyst formation in ADPKD, linking cilia and polycystin-1 function.

This study develops a Tumor-on-Chip platform for rapid drug testing in breast cancer, showing high concordance with patient-derived xenografts and potential for clinical use.

This study introduces magnetic bioprinting to control tissue geometry and mechanical forces in skeletal muscle, enabling shape fabrication and mechanical property investigation.

This paper applies magnetite nanoparticle photothermal therapy in a pancreatic tumor-on-chip model to target cancer cells and their microenvironment, showing increased cell death and matrix changes.

This study uses a kidney-on-chip model to decouple shear stress and pressure effects on tubule dilation in Pkd1-/- cells, revealing distinct mechanisms in different kidney cell types.

This study develops a magnetic bioprinting method to create stretchable, shape-controlled skeletal muscle tissues that maintain their form and enhance maturation through magnetic stimulation.

This study shows PIEZO channels are essential for intestinal stem cell maintenance by sensing mechanical cues from their niche.

The paper introduces a magnetic microtweezer system for bioseparation in sub-nanoliter droplets, achieving 72% extraction efficiency for oligonucleotides.