The paper identifies pupal metamorphosis as a critical stage for RNA virus persistence in Drosophila, revealing distinct viral strategies involving reverse transcription and immune responses.

bioRxiv · Nov 7, 2025 · PreprintMicrobiology

Spatiotemporal factors shape mosquito virus diversity and virome composition in a host and virus-dependent manner

Cassandra Koh, Lionel Frangeul, Hervé Blanc, Aurélien Gibaud, Annabelle Henrion-Lacritick, Rohit A. Chitale, Sébastien Boyer, Jean‐Bernard Duchemin, Philippe Dussart, Romain Girod, Nina Grau, Carine Ngoagouni, Anamarija Butković, Maria‐Carla Saleh

The paper examines how host and ecological factors shape mosquito virome diversity and composition across different regions and time periods.

bioRxiv · Sep 5, 2025 · PreprintMicrobiology

Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti

Alexander Bergman, Anna Beth Crist, Hélène Lopez-Maestre, Hervé Blanc, Mauro Castelló-Sanjuán, Lionel Frangeul, Hugo Varet, Josquin Daron, Sarah Hélène Merkling, Maria‐Carla Saleh, Louis Lambrechts

The study investigates the role of the siRNA pathway in regulating transposable element expression in Aedes aegypti, finding limited impact in both somatic and gonadal tissues.

bioRxiv · Nov 26, 2024 · PreprintGenomics

Decoding rRNA Sequences for Improved Metagenomics in Sylvatic Mosquito Species

Cassandra Koh, Lionel Frangeul, Hervé Blanc, Carine Ngoagouni, Sébastien Boyer, Philippe Dussart, Nina Grau, Romain Girod, Jean‐Bernard Duchemin, Maria‐Carla Saleh

The paper develops rRNA sequences for 33 medically important mosquito species to improve metagenomics and species identification in mosquito-borne virus surveillance.

eLife · Jan 23, 2023Peer-reviewedBioinformatics