Hugo Varet

The paper shows capsule exchange in Klebsiella pneumoniae has minimal fitness costs and preserves virulence traits across genetic backgrounds, suggesting plug-and-play dynamics in capsule loci.

This study identifies ITGB1 and MRC2 as host factors involved in bronchial epithelial cell antifungal activity through interactions with A. fumigatus lectin FleA, revealing two pathways that inhibit fungal filamentation.

This study uses live imaging to show that Duchenne Muscular Dystrophy mouse model MuSCs have impaired migration and premature differentiation due to altered signaling pathways, with intrinsic and extracellular factors influencing their behavior.

This study shows that the K-D-K-E motif in RABV L protein's methyltransferase domain is crucial for immune evasion by altering viral and host RNA methylation, increasing sensitivity to interferon, and reducing pathogenicity.

This study identifies a cytochrome P450 gene variant that influences dengue virus susceptibility in Aedes aegypti mosquitoes.

This study challenges the assumed antiviral role of Vago genes in Aedes aegypti by showing that VLG-1 has a modest proviral effect during DENV and ZIKV infections.

The paper shows that vimentin absence in glioblastoma cells affects nuclear mechanotransduction, DNA damage response, and cell survival under stress.

This study investigates two mutations in M. tuberculosis B0/W148 clone, finding they do not impair growth or virulence but alter transcriptional profiles.

The study investigates the role of the siRNA pathway in regulating transposable element expression in Aedes aegypti, finding limited impact in both somatic and gonadal tissues.

This study identifies Prosaposin as a regulator of neural stem cell quiescence in zebrafish, showing it maintains deep quiescence and reduces activation.

ChIPflow is a pipeline for epigenomic data analysis from raw data to differential analysis, showing that statistical settings affect results depending on chromatin factor dynamics and variability.

The paper identifies HP1γ's RNA binding activity in transcribed genes and shows it enhances splicing fidelity by tethering pre-mRNA to chromatin through intronic repeats.