Jianmin Wu

This study shows that introgression is widespread across oak phylogeny and affects gene expression through cis-regulation and DNA methylation decay.

The paper constructs a single-cell atlas of the human lung across the lifespan, identifying new cell types and regenerative mechanisms linked to lung diseases.

DeepAden predicts A-domain substrate specificities in NRPSs using a two-stage deep learning framework, achieving competitive performance and enabling the identification of novel NRP gene clusters.

This study determines cryo-EM structures of B0AT2 to elucidate substrate recognition and allosteric inhibition mechanisms, revealing conserved intracellular cavities across SLC6 transporters.

scTrends classifies and quantifies gene expression trends along pseudotime in single-cell RNA-seq datasets, revealing diverse expression patterns across biological processes.

The paper constructs a graph-based pangenome for pear to identify genetic variants associated with climate-resilient and horticultural traits.

This study identifies p300/CBP-mediated acetylation of PARP7 as a mechanism to suppress IFN-I signaling in tumor cells, with implications for enhancing antitumor immunity.