Ying Wang

This study identifies p300/CBP-mediated acetylation of PARP7 as a mechanism to suppress IFN-I signaling in tumor cells, with implications for enhancing antitumor immunity.

The paper develops PoLixNano nanoparticles using machine learning to enhance mRNA delivery through nebulization, achieving high transfection efficiency and therapeutic efficacy in animal models.

This study uses base editing in goat embryos to introduce nonsense mutations in FGF5, improving cashmere yield with minimal off-target effects.