BiochemistrybioRxivPreprint
Breaking β-sheets in FUS prion-like domain preserves phase separation and function but prevents aggregation and toxicity
Noah Wake, Juan Alcalde, Daniel Jutzi…·Nicolas Lux Fawzi
This study introduces β-sheet breaking proline residues into FUS prion-like domain to prevent aggregation and toxicity while preserving phase separation and function.
2 citations