Loss of Fanconi anemia proteins causes a reliance on lysosomal exocytosis
Becky Xu Hua Fu, Albert Xu, Hua Li, Daniel E. Johnson, Jennifer Rubin Grandis, Luke A. Gilbert
This study identifies a dependency on lysosomal exocytosis in FA pathway-deficient cells and tumors, revealing a new therapeutic target for FA-related cancers.
Cell Death and Disease · Nov 4, 2025Peer-reviewedCell Biology