Arterial cells support the development of human hematopoietic progenitors in vitro via secretion of IGFBP2.
Paolo Petazzi, Telma Ventura, Francesca Paola Luongo, Alisha May, Helen Alice Taylor, Nicola Romanò, Lesley M. Forrester, Pablo R. Menéndez, Antonella Fidanza
The paper identifies IGFBP2 as a key factor secreted by arterial cells that enhances hematopoietic progenitor development in vitro.
bioRxiv · Oct 4, 2022 · PreprintDevelopmental Biology