MicrobiologyPLoS PathogensPeer-reviewed
Capture of fusion-intermediate conformations of SARS-CoV-2 spike requires receptor binding and cleavage at either the S1/S2 or S2' site
Sabrina Lusvarghi, Russell A. Vassell, Brittany Williams…·Carol D. Weiss
This paper investigates fusion-intermediate conformations of SARS-CoV-2 spike by using an HR2 peptide inhibitor, showing that receptor binding and cleavage at S1/S2 or S2' sites are required to capture these intermediates.