Cancer BiologyTranslational OncologyPeer-reviewed
SMARCA4, STK11, and KEAP1 co-inactivation associates with poor prognosis and upregulation of the TGF-β pathway in lung adenocarcinoma
Emily A. Costa, Barbara Vaz de Mello, Corrin A. Wohlhieter…·Charles M. Rudin
The paper identifies SMARCA4/STK11/KEAP1 triple mutant lung adenocarcinoma as a poor prognosis subset and links it to TGF-β pathway activation.
DOI 10.1016/j.tranon.2026.102915