Author

Li Chen

Princeton UniversityORCID 0000-0002-1108-7645Unclaimed ORCID profile · follow to get notified of new preprints

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Li Chen14 papers · Northwestern University

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew D. MathisiD· 1 shared Andrew F. SchoberiD· 1 shared Christine IngleiD· 1 shared Ivan JunieriD· 1 shared Joshua D. RabinowitziD· 1 shared Junyoung O. ParkiD· 1 shared Kimberly A. ReynoldsiD· 1 shared Olivier RivoireiD· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperSystems Biology

Andrew D. MathisORCID

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1 paper

Recent·Most cited

A two-enzyme adaptive unit in bacterial folate metabolism

Andrew F. Schober, Andrew D. Mathis, Christine Ingle, Junyoung O. Park, Li Chen, Joshua D. Rabinowitz, Ivan Junier, Olivier Rivoire, Kimberly A. Reynolds

The paper investigates adaptive dependencies between enzymes in bacterial folate metabolism, showing that DHFR and TYMS form a modular unit that can adapt independently from the rest of the genome.

Cell Reports · Jun 1, 2019Peer-reviewedSystems Biology