Author

Caryn Willis

RTI InternationalORCID 0000-0002-1117-8395Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Bryan C. QuachiD· 2 shared Eric Otto JohnsoniD· 2 shared An T. Hoang· 1 shared Bibi S. Kassim· 1 shared Bradley Todd WebbiD· 1 shared Brion S. MaheriD· 1 shared Chesna Apere· 1 shared Chidera OkekeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Bryan C. QuachORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Heterogeneous epigenetic variation converges on splicing dysregulation in opioid addiction

Fatir A. Qureshi, Chesna Apere, Chidera Okeke, Bibi S. Kassim, Marina Iskhakova, Richard C. Sallari, Maharshi Chakraborty, Laura Morgan, Zia Barnard, Xochitl Luna, Megan Madden, Pavanna G. Rotti, An T. Hoang, Hannah K. Ramcharan, Bryan C. Quach, , Olivia Corradin

This study identifies epigenetic variation linked to opioid overdose using H3K27ac profiling and machine learning, revealing splicing dysregulation and CELF5 as a key factor.

medRxiv · Dec 29, 2025 · PreprintGenetic & Genomic Medicine

Identifying compounds to treat opiate use disorder by leveraging multi-omic data integration and multiple drug repurposing databases.

Jeran K. Stratford, Megan Ulmer Carnes, Caryn Willis, Melyssa S. Minto, Logain Elnimeiry, Ravi Mathur, Matthew C. Schu, Bryan C. Quach, Javan K. Carter, Tracy L. Nolen, Nathan Vandergrift, Thomas R. Kosten, Eric Otto Johnson, Bradley Todd Webb

The paper identifies FDA-approved drugs targeting genes associated with opioid use disorder by integrating multi-omic data and drug databases.

Translational Psychiatry · Nov 21, 2025Peer-reviewedGenetic & Genomic Medicine