Author

Carlo D. Manno

Rush University Medical CenterORCID 0000-0002-1120-9606Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Adolfo López de MunainiD· 1 shared Ainara Vallejo‐IllarramendiiD· 1 shared Eshwar Reddy TammineniiD· 1 shared Lourdes FigueroaiD· 1 shared Maialen Sagartzazu‐AizpuruaiD· 1 shared Michael FilliD· 1 shared Pablo Marco‐MorenoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPhysiology

Adolfo López de MunainORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

PhysiologyAmerican Journal of Physiology-Cell PhysiologyPeer-reviewedMay 19, 2026

Disrupting the Feed-Forward Cycle of RyR1 Calcium Leak and Oxidative Stress Mitigates Doxorubicin-Induced Skeletal Myopathy

Lourdes Figueroa, Eshwar Reddy Tammineni, Pablo Marco‐Moreno…·Carlo D. Manno

This study shows that doxorubicin causes skeletal muscle weakness by disrupting RyR1 calcium leak and oxidative stress, and that stabilizing the RyR1-FKBP12 complex with triazole compounds mitigates these effects.

DOI 10.1152/ajpcell.00938.2025

mouseexperimental assay

𝕏 PostBluesky