Exploration of mRNA-sized RNA import into Saccharomyces cerevisiae mitochondria by a combined synthetic biology and adaptive laboratory evolution approach
Charlotte C. Koster, Kavish A.V. Kohabir, Maxime den Ridder, Marijke A. H. Luttik, Erik A. F. de Hulster, Martin Pabst, Pascale A. S. Daran-Lapujade
This study investigates RNA import into yeast mitochondria using synthetic biology and adaptive laboratory evolution, finding that mRNA import remains undemonstrated despite existing short RNA import mechanisms.
bioRxiv · Aug 28, 2025 · PreprintSynthetic Biology