Martin Pabst

The paper shows glycogen-accumulating organisms use the ethylmalonyl-CoA pathway for CO2 fixation to achieve metabolic parity with polyphosphate-accumulating organisms, leading to community shifts through stoichiometric advantages.

The paper describes a protocol for producing 13C-labelled yeast extract as an internal standard for metabolomics and quantifying intracellular metabolites.

SugarBase identifies microbial nucleotide sugar profiles, revealing species-specific and previously unannotated sugars, and expands antimicrobial targets.

NovoGlyco identifies novel protein glycosylation in prokaryotes using shotgun proteomics data, revealing previously unreported flagella O-glycans in Campylobacter fetus.

This study identifies Avs5 systems as a conserved bacterial defense against jumbo phages, revealing their mechanism of recognizing and disrupting phage infection.

This study identifies key microbial species and metabolic pathways in high-performing biofilm-based microbial electrosynthesis systems and provides insights into their community dynamics and product formation.

The paper develops a wastewater metaproteomics approach to identify microbial and human protein biomarkers from wastewater samples over three months.

Meta-PepView evaluates and visualizes metaproteomics data through a web-based platform, offering modular design and open-source access.

This study compares D- and L-lactate consumption by gut microbes, finding distinct microbial communities and metabolic pathways for each isomer.

This study investigates RNA import into yeast mitochondria using synthetic biology and adaptive laboratory evolution, finding that mRNA import remains undemonstrated despite existing short RNA import mechanisms.

The paper develops a metabolomics workflow to measure temporal variations in nucleotide pools in EBPR biofilms, revealing dynamic changes in energy charge during metabolic processes.

This study uses long-term multi-meta-omics to identify the ecophysiological controls of seasonal N2O emissions in wastewater treatment systems.

The paper combines microbial enrichment with metagenomics and metaproteomics to identify novel glycoside hydrolases from complex environments.

This paper introduces a microfluidic platform for extracting and analyzing bacterial genomic DNA without fragmentation, demonstrating its use on B. subtilis cells.

The paper shows clade II N2O-reducers outcompete clade I under low N2O availability, and coexist under high N2O, with cobalamin interactions influencing community composition.

The paper uses metaproteomic approaches to analyze the extracellular proteome of a granular Candidatus Accumulibacter enrichment, identifying proteins involved in biofilm formation.

This study shows two Aeromonas strains can degrade and use chitin as a carbon and nitrogen source, revealing their metabolic potential in nutrient-poor environments.

NovoLign provides a de novo metaproteomics pipeline for rapid taxonomic profiling and reference database creation, offering an alternative to database-based spectral annotation.

The paper compares metaproteomic and genomic approaches to study the aerobic granular sludge microbiome, highlighting differences in insights and the importance of reference databases.

This study quantifies proteome dynamics in yeast during the transition from exponential to stationary phase under aerobic and anaerobic conditions, revealing significant differences in proteome changes between the two environments.

The paper compares proteomes of three Saccharomyces cerevisiae strains grown on sucrose and glucose, finding Mnp1 is consistently higher on sucrose and opposite biological function patterns between strains.

This study evaluates yeast sample preparation protocols for proteomics, finding that urea with filter-aided or in-solution digestion provides best coverage, while solvents like acetone introduce artefacts.

This study compares two metabolite extraction methods for yeast, finding that cold-solvent extraction underestimates phosphorylated sugars and nucleotides, while methanol-quenching with boiling-ethanol-extraction provides more accurate quantification.

The paper investigates why iron-sulphur cluster enzymes are often inactive when heterologously expressed in E. coli and identifies strategies to improve their functionality.

The paper investigates lipolytic bacteria and extracellular lipases in low-temperature anaerobic reactors using metagenomics and metaproteomics, finding limited correlation between lipase abundance and reactor conditions.

This study successfully humanizes the entire glycolytic pathway in yeast, revealing conserved functions and context-dependent responses.

This paper introduces a mass binning glycoproteomics approach to explore prokaryotic protein glycosylation, revealing unique surface layer modulation in an anammox bacterium.

This paper introduces a de novo metaproteomics pipeline and validation strategy to enable quantitative profiling of microbial communities without relying on sequence databases.