Pabitra K. Parua

This study shows that H2Bub1 regulates the transition from elongation to termination in RNA Pol II transcription by modulating Cdk9 and PP1 activity near gene 3-ends.

The paper identifies two Cdk9-phosphatase switches that regulate RNA polymerase II elongation and termination by modulating Spt5 phosphorylation at different stages of transcription.

The paper identifies a Cdk9-PP1 kinase-phosphatase switch that regulates the transition of RNA polymerase II from elongation to termination by modulating Spt5 phosphorylation.

This study investigates the role of Cdk9 in regulating RNA Polymerase II elongation rate using fission yeast and PRO-seq, finding that Cdk9 inhibition severely impairs early transcription but allows continued elongation.

The paper investigates the interaction between Cdk9, H2Bub1, and the Clr6-CII HDAC complex in regulating antisense and sense transcription in fission yeast.