Author

Samuele Zilioli

Wayne State UniversityORCID 0000-0002-1126-8913Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:differential expression· 4 Approach:statistical model· 4 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Assay:scATAC-seq· 2 Assay:scRNA-seq· 2 Research Focus:eQTL / molecular QTL mapping· 1

Frequent Co-Authors

Adnan AlaziziiD· 5 shared Francesca LucaiD· 5 shared Henriette E. Mair-MeijersiD· 5 shared Roger Piqué-RegiiD· 5 shared Julong Wei· 4 shared Justyna ResztakiD· 4 shared Richard Bennett SlatcheriD· 4 shared Xiaoquan WeniD· 4 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Adnan AlaziziORCID

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5 papers

Recent·Most cited

Psychological stress and social support are associated with opposing single-cell pro-inflammatory gene regulatory mechanisms in adults

Ali Ranjbaran, Cindy Kalita, Julong Wei, Kristin M. Davis, Julian Bruinsma, Henriette E. Mair-Meijers, Gabrielle Garlicki, Adnan Alazizi, Michael C. Petriello, Yanping Jiang, Samuele Zilioli, Roger Piqué-Regi, Francesca Luca

The paper identifies opposing gene regulatory mechanisms in CD4+ T cells and monocytes associated with psychological stress and social support in African American adults using scRNA-seq and scATAC-seq.

bioRxiv · Oct 14, 2025 · PreprintGenomics

Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts

Julong Wei, Justyna Resztak, Ali Ranjbaran, Adnan Alazizi, Henriette E. Mair-Meijers, Richard Bennett Slatcher, Samuele Zilioli, Xiaoquan Wen, Francesca Luca, Roger Piqué-Regi

The paper uses scATAC-seq to analyze chromatin accessibility and gene expression dynamics in immune cells from asthmatic children, identifying eQTLs and their regulatory roles in asthma risk.

The American Journal of Human Genetics · Jan 14, 2025Peer-reviewedGenomics

Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single cell resolution

Justyna Resztak, Julong Wei, Samuele Zilioli, Edward D. Sendler, Adnan Alazizi, Henriette E. Mair-Meijers, Peijun Wu, Xiaoquan Wen, Richard Bennett Slatcher, Xiang Zhou, Francesca Luca, Roger Piqué-Regi

The paper uses single-cell RNA-seq to study how genetic variants influence the transcriptional response to glucocorticoids and immune stimuli in children, identifying treatment-specific gene regulation.

Genome Research · Jun 1, 2023Peer-reviewedGenomics

Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma

Justyna Resztak, Jane Choe, Shreya Nirmalan, Julong Wei, Julian Bruinsma, Russell Houpt, Adnan Alazizi, Henriette E. Mair-Meijers, Xiaoquan Wen, Richard Bennett Slatcher, Samuele Zilioli, Roger Piqué-Regi, Francesca Luca

The paper identifies gene expression changes in immune cells during pubertal development in children with asthma, showing shifts in immunity and correlations with asthma-related gene expression.

Nature Communications · Jan 16, 2023Peer-reviewedGenomics

Psychosocial experiences modulate asthma-associated genes through gene-environment interactions

Justyna Resztak, Allison K. Farrell, Henriette E. Mair-Meijers, Adnan Alazizi, Xiaoquan Wen, Derek E. Wildman, Samuele Zilioli, Richard Bennett Slatcher, Roger Piqué-Regi, Francesca Luca

The paper identifies 174 asthma-associated genes regulated by psychosocial factors and 349 gene-environment interactions using RNA-sequencing and machine learning in children with asthma.

eLife · Jun 18, 2021Peer-reviewedGenomics