Justyna Resztak

This study identifies a remodeled neutrophil state associated with meibomian gland dysfunction, showing IFN-γ and PAD4-dependent obstruction in mice.

The paper uses scATAC-seq to analyze chromatin accessibility and gene expression dynamics in immune cells from asthmatic children, identifying eQTLs and their regulatory roles in asthma risk.

The paper integrates GWAS and multi-omic QTLs to identify gene-biotype and phenotype associations related to COVID-19, revealing pleiotropy and causal links.

The paper uses single-cell RNA-seq to study how genetic variants influence the transcriptional response to glucocorticoids and immune stimuli in children, identifying treatment-specific gene regulation.

The paper identifies gene expression changes in immune cells during pubertal development in children with asthma, showing shifts in immunity and correlations with asthma-related gene expression.

The paper identifies 138 genes differentially expressed in blood immune cells associated with poverty, enriched in wound healing and coagulation, and linked to hypertension.

The paper investigates how interspecies variation in hominid gut microbiota affects host gene regulation in colonic epithelial cells, finding species-specific gene responses linked to inflammatory diseases.

The paper identifies 174 asthma-associated genes regulated by psychosocial factors and 349 gene-environment interactions using RNA-sequencing and machine learning in children with asthma.