Ellen A. Lumpkin

OCTRON provides a segmentation and tracking pipeline for behavioral experiments, validated across species and setups.

The paper uses in vivo imaging to show that somatosensory axons and Merkel cells undergo dynamic remodeling during epidermal homeostasis, with axons showing plasticity even when Merkel cells are stable.

The paper identifies five functionally distinct mechanosensory neuron subsets in the mouse tongue using in vivo calcium imaging and clustering analysis of their response profiles to mechanical stimuli.

The paper investigates the distribution of TRP channels in human oral tissues to understand their role in environmental sensing.

This study identifies previously undescribed afferent endings in human oral tissues and describes their anatomical organization for mechanosensory functions.

This study identifies sphingosine 1-phosphate and its receptor S1PR3 as critical regulators of mechanical pain by modulating mechanonociceptor excitability.

This study shows 2-APB inhibits keratinocyte proliferation and reduces cSCC growth in vitro by promoting differentiation and altering calcium signaling.