Author

Aoneng Cao

Shanghai UniversityORCID 0000-0002-1168-3623Unclaimed ORCID profile · follow to get notified of new preprints

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Biochemistry· 1

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Approach:experimental assay· 1

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Haifang WangiD· 1 shared Jiewen DengiD· 1 shared Tiange GaoiD· 1 shared Tongtong ZhouiD· 1 shared Yan WangiD· 1 shared Yi CaoiD· 1 shared Yuanyuan LiuiD· 1 shared Yuye Cao· 1 shared

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1 shared paperBiochemistry

Haifang WangORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintJun 26, 2025

An efficient artificial esterase with a dynamic conformation via conformational engineering

Yan Wang, Yi Cao, Yuanyuan Liu…·Aoneng Cao

This study creates an artificial esterase with enhanced catalytic efficiency by engineering dynamic active centers, achieving a kcat 5-fold higher than natural chymotrypsin.

DOI 10.1101/2025.06.26.661850

experimental assay

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