BiochemistrybioRxivPreprint
An efficient artificial esterase with a dynamic conformation via conformational engineering
Yan Wang, Yi Cao, Yuanyuan Liu…·Aoneng Cao
This study creates an artificial esterase with enhanced catalytic efficiency by engineering dynamic active centers, achieving a kcat 5-fold higher than natural chymotrypsin.
DOI 10.1101/2025.06.26.661850