GenomicsbioRxivPreprint
Joint profiling of 5mC, 5hmC, and the transcriptome in single cells identifies factors responsible for genome-wide DNA methylation erasure in human primordial germ cell maturation
Alex Chialastri, Kellie A. Heom, Joanna J. Gell…·Siddharth S. Dey
The paper introduces scMHT-seq, a single-cell method to profile 5mC, 5hmC, and transcriptomes, revealing DNA methylation erasure mechanisms in human primordial germ cell maturation.
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