Microglial P2Y6 calcium signaling promotes phagocytosis and shapes neuroimmune responses in epileptogenesis
Anthony D. Umpierre, Bohan Li, Katayoun Ayasoufi, Whitney L. Simon, Shunyi Zhao, Manling Xie, Grace Thyen, Benjamin Hur, Jiaying Zheng, Yue Liang, Dale B. Bosco, Mark Andrew Maynes, Zhaofa Wu, Xinzhu Yu, Jaeyun Sung, , Long‐Jun Wu
The paper identifies UDP-P2Y6 signaling as a key driver of microglial calcium activity, phagocytosis, and neuroinflammation during epileptogenesis.
Neuron · Apr 12, 2024Peer-reviewedNeuroscience