Structural Insights into the Expanded Substrate Scope of a Cysteine-Dependent Hydrolase from Rhodococcus opacus for Polyethylene, Polypropylene, and Polystyrene Biodegradation
Shubham Aggarwal, Saurabh Singh, Arpan Kayastha, Divya Aggarwal, Kuldeep Jangid, Mohammad Shakib, Deepika Singh, Ashwani Kumar Sharma, Pravindra Kumar
This study determines the crystal structures of a cysteine-dependent hydrolase from Rhodococcus opacus in complex with various plastics and shows its ability to degrade polyethylene, polypropylene, and polystyrene.
bioRxiv · Oct 9, 2026 · PreprintBiophysics