Pharmacology & ToxicologyBioorganic & Medicinal Chemistry LettersPeer-reviewed
Design and Biophysical Characterization of Second-Generation Cyclic Peptide LAG-3 Inhibitors for Cancer Immunotherapy
Laura Calvo‐Barreiro, Longfei Zhang, Yasir Ali…·Moustafa Tarek Gabr
The paper designs and characterizes second-generation cyclic peptide LAG-3 inhibitors, identifying cyclic peptide 12 as the most effective with an IC50 of 4.45 µM.