BiochemistrybioRxivPreprint
Hsp90-dependent triage of the glucocorticoid receptor via the CHIP E3 ubiquitin ligase
Cynthia M. Chio, Feng Wang, Chari M. Noddings, David A. Agard
This study demonstrates that Hsp90 presents the glucocorticoid receptor to the CHIP E3 ubiquitin ligase for degradation during its folding cycle.