Tongjin Wu

DynaKiller-Scan characterizes single-cell killing dynamics and molecular signatures in cytotoxic lymphocytes, revealing differences in kinetics and cytokine responses between CD4+ and CD8+ CAR-T cells.

The paper introduces MEDAL, a microfluidic platform for high-throughput T cell epitope screening by producing DNA-barcoded APCs loaded with peptides, enabling efficient identification of MHC-binding peptides.