Lih Feng Cheow

DynaKiller-Scan characterizes single-cell killing dynamics and molecular signatures in cytotoxic lymphocytes, revealing differences in kinetics and cytokine responses between CD4+ and CD8+ CAR-T cells.

The paper introduces scComplete-seq, a method to profile non-polyadenylated RNA in single cells, revealing changes in coding and non-coding transcriptomes and enhancer RNA activity in PBMCs.

The paper introduces MEDAL, a microfluidic platform for high-throughput T cell epitope screening by producing DNA-barcoded APCs loaded with peptides, enabling efficient identification of MHC-binding peptides.

This study develops a single-nucleus CUT&RUN assay to analyze histone modifications in HNSCC cell lines, revealing how epigenetic changes contribute to cancer progression and heterogeneity.