Developmental BiologybioRxivPreprint
Tartrate-resistant acid phosphatase (TRAP/ACP5) sex-specifically regulates bone maintenance in old mice, but the anabolic effects of mechanical loading is regulated in a sex-independent way
Bhavik Rathod, Hasmik Jasmine Samvelyan, Nicole Gustafsson…·Sara H. Windahl
This study shows TRAP regulates sex-specific bone maintenance and mechanical loading responses in old mice, with TRAP-deficiency impairing bone formation in both sexes.
DOI 10.1101/2025.09.03.673915