Author

Jonas Fuxe

Karolinska InstitutetORCID 0000-0003-4576-9377Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Wenyang ShiiD· 2 shared Anastasia Bazioti· 1 shared Andrea Rodgers FuronesiD· 1 shared Aneta LiszkaiD· 1 shared Anna FahlgreniD· 1 shared Bhavik RathodiD· 1 shared Claes OhlssoniD· 1 shared Dhifaf SarhaniD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersImmunology

Wenyang ShiORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintSep 3, 2025

Tartrate-resistant acid phosphatase (TRAP/ACP5) sex-specifically regulates bone maintenance in old mice, but the anabolic effects of mechanical loading is regulated in a sex-independent way

Bhavik Rathod, Hasmik Jasmine Samvelyan, Nicole Gustafsson…·Sara H. Windahl

This study shows TRAP regulates sex-specific bone maintenance and mechanical loading responses in old mice, with TRAP-deficiency impairing bone formation in both sexes.

DOI 10.1101/2025.09.03.673915

mouseexperimental assay

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ImmunologyCancer Immunology ResearchPeer-reviewedApr 28, 2025

Enhanced NK cell proficiency in solid tumors through antigen-specific memory via NKG2C/A-HLA-E/ABC recruited to tumors by CXCR2

Yizhe Sun, Andrea Rodgers Furones, Okan Gultekin…·Dhifaf Sarhan

This study shows that antigen-specific memory NK cells can be generated in ovarian cancer, enhancing their cytotoxicity and tumor reactivity through NKG2C/A-HLA-E/ABC interactions and CXCR2-mediated migration.

28 citationstop 1%

humanbulk RNA-seq

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Cancer BiologybioRxivPreprintMar 17, 2025

Podoplanin-Linked Mesenchymal Shift Synergizes with CCR7 driving Lymphatic Metastasis and Tumor Progression in Breast Cancer

Zhi Wang, Lise Martine Ingebriktsen, Tove Bekkhus…·Maria Helena Ulvmar

The paper identifies a synergistic role between CCR7 and PDPN-driven mesenchymal shift in promoting lymphatic metastasis and tumor progression in breast cancer.

DOI 10.1101/2025.03.17.643704

humanbulk RNA-seq

𝕏 PostBluesky