Author

Tomohiko Akiyama

Keio UniversityORCID 0000-0002-1238-8095Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Kei‐ichiro IshiguroiD· 2 shared Minoru S.H. KoiD· 2 shared Akihiko SakashitaiD· 1 shared Alexis MorrisseyiD· 1 shared Atsushi SuzukiiD· 1 shared B. Franklin PughiD· 1 shared Chisato KoderaiD· 1 shared Daniela Q. JamesiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersDevelopmental Biology

Kei‐ichiro IshiguroORCID

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedMar 30, 2026

Functional redundancy between UTY and UTX in regulating the localization of transcription factors involved in pluripotency

Tomohiko Akiyama, Toshiya Nakahara, Saeko Sato…·Minoru S.H. Ko

This study shows UTY and UTX work together to maintain gene regulation in human stem cells by supporting transcription factor localization and chromatin accessibility.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 6, 2023

Joint sequence & chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin

Sonny Arora, Jianyu Yang, Tomohiko Akiyama…·Shaun Mahony

The paper investigates how sequence preferences and chromatin environments influence Fox TF binding using neural networks and mouse stem cells.

8 citations

mouseChIP-seq

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Developmental BiologybioRxivPreprintJan 15, 2021

Meiosis-specific ZFP541 repressor complex promotes meiotic prophase exit during spermatogenesis

Yuki Takada-Horisawa, Chisato Kodera, Kazumasa Takemoto…·Kei‐ichiro Ishiguro

This study identifies a ZFP541-KCTD19 repressor complex that promotes meiotic prophase exit in spermatogenesis by suppressing transcriptional regulators and chromatin modifiers.

1 citation

mouseChIP-seq

𝕏 PostBluesky