GeneticsPLoS PathogensPeer-reviewed
Intranasal gene therapy to prevent infection by SARS-CoV-2 variants
Joshua J. Sims, Jenny A. Greig, Kristofer T. Michalson…·James M. Wilson
This paper demonstrates an intranasal gene therapy approach using an affinity-matured ACE2 decoy protein to prevent SARS-CoV-2 infection and its variants in animal models.
46 citations