Author

Jenny A. Greig

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:non-human primate· 2 Organism:mouse· 1

Frequent Co-Authors

James M. WilsoniD· 2 shared Camilo Ayala BretoniD· 1 shared Cecilia DyeriD· 1 shared Christian J. Hinderer· 1 shared Hanying YaniD· 1 shared Jason LamontagneiD· 1 shared Jessica A. ChichesteriD· 1 shared Jingxu Zhu· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

James M. WilsonORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of transgene expression limits liver gene therapy in primates

Jenny A. Greig, Kelly M. Martins, Camilo Ayala Breton, Jason Lamontagne, Yanqing Zhu, Zhenning He, John White, Jingxu Zhu, Jessica A. Chichester, Qi Zheng, Zhe Zhang, Peter L. Bell, Lili Wang, James M. Wilson

This study shows that transgene expression in primate liver declines rapidly after initial transduction, even though vector DNA remains in the nucleus, suggesting that genomic integration may be needed for durable expression.

Nature Biotechnology · Nov 6, 2023Peer-reviewedMolecular Biology

Intranasal gene therapy to prevent infection by SARS-CoV-2 variants

Joshua J. Sims, Jenny A. Greig, Kristofer T. Michalson, Sharon Lian, R. Alexander Martino, Rosemary Meggersee, Kevin B. Turner, Kalyani Nambiar, Cecilia Dyer, Christian J. Hinderer, Makoto Horiuchi, Hanying Yan, Xin Huang, Shu‐Jen Chen, James M. Wilson

This paper demonstrates an intranasal gene therapy approach using an affinity-matured ACE2 decoy protein to prevent SARS-CoV-2 infection and its variants in animal models.

PLoS Pathogens · Jul 15, 2021Peer-reviewedGenetics