Valerie Horsley

This study identifies SUN2 as a mediator of nuclear mechanosensing in fibrosis, showing it drives chromatin remodeling and fibrotic gene expression in response to mechanical stiffness.

This study shows that loss of Sun2 reduces extracellular matrix production and prevents lung fibrosis by disrupting nuclear mechanosensing.

This paper identifies age-dependent metabolic reprogramming in wound macrophages driven by niche secreted signals using multi-omics approaches.

This study examines how macrophages respond transcriptionally to efferocytosis in mouse skin wounds, finding both pro-repair and inflammatory responses depending on context.

The paper profiles single-cell RNA sequencing data from diabetic foot ulcers to identify cell types and gene expression patterns associated with wound healing.